ClearPath Diagnostics provides highly specialized gynecologic pathology services to referring clinicians. Our gynecologic section offers in depth expertise in the interpretation of Pap tests and gynecologic tissue specimens. We have been at the forefront in providing new advances in diagnostic technology for the benefit of your patients.

We are an independent laboratory that focuses on outreach anatomical pathology services. We offer highly accurate diagnostics with rapid turn around of cases and personalized service. ClearPath prides itself on establishing excellent communication with all health care providers.

Tissue pathology

Our pathologists have extensive experience in the interpretation of gynecologic specimens. They are always on site and available to handle calls and questions.

Photographs to supplement the diagnostic report are available on selected reports or if requested. Our pathologists also actively participate in teaching and investigative studies in gynecologic fields.


Our modern and innovative laboratory is the largest for cytology screening services in the region. We have a well-trained and experienced team of cytotechnologists that complement our pathologists, providing maximum skill in Pap test evaluation.

We were the first in upstate New York to introduce ThinPrep® monolayer technology to enhance the sensitivity and reliability of Pap screening. We were also the first in the region to implement image assisted, computerized pre-screening of all Pap tests which helps to ensure that no abnormal cells are overlooked.

HPV (Human papillomavirus) evaluation

In addition, we led the way in offering the Hologic Cervista® Human papillomavirus (HPV) assay with genotyping which uses Invader® Technology to test for 14 high risk HPV types. Furthermore, Cervista HPV 16/18 individually identifies and differentiates high risk types 16 and 18 which are the two most highly oncogenic and persistent high risk HPV types known to cause high grade cervical dysplasia and approximately 70% of all cervical cancers. This test can be performed from the ThinPrep specimen vial, and is FDA approved. ThinPrep Pap specimens must be less than three weeks old. HPV testing can be done reflexively on all ThinPrep Pap samples. There must be sufficient quantity remaining after processing the pap test to perform the testing. Also, tissue specimens (paraffin embedded) can be tested for high and low risk HPV using in situ hybridization. Tissue specimens are stable indefinitely.

Neisseria gonorrhea, Chlamydia trachomatis and Trichomonas vaginalis testing from ThinPrep vial

ClearPath offers Neisseria gonorrhoeae and Chlamydia trachomatis testing using the highly sensitive Hologic Gen-Probe® APTIMA Combo 2® Assay and Trichomonas vaginalis testing using the Hologic Gen-Probe APTIMA Trichomonas vaginalis Assay. These tests can be done using the ThinPrep liquid Pap specimen that is also sent for Pap and HPV analysis. This method allows us to provide up to 5 results (Pap, HPV, GC/Chlamydia and Trichomonas) from a single specimen, minimizing specimen handling for collection and transportation. To do these tests in conjunction with a ThinPrep Pap, they must be ordered along with the Pap. GC/Chlamydia and Trichomonas testing cannot be performed after the aliquot for the Pap test has been taken from the vial. Specimen collection and transport information for Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis testing can be found here. We provide the collection and transport material.

Vaginitis Testing

We offer triple testing for Candida species, Gardnerella vaginalis and Trichomonas vaginalis using Becton Dickinson AffirmTM, VPIII for these agents. This analysis requires a separate vaginal swab. We provide the special swabs and transport system. The tests that comprise the Affirm Panel cannot be ordered individually from this test.

Molecular Diagnostic-PCR Testing

We offer molecular diagnostic testing through an exclusive arrangement with Medical Diagnostic Laboratories. This advanced polymerase chain reaction (PCR) technique provides a highly sensitive and specific test for numerous pathogens. All tests can be performed from one specimen, collected with MDL's OneSwab®.

Group B Streptococcus Testing

ClearPath Diagnostics is the first in the region to offer the illumigene® test for Group B Streptococcus (GBS). This new assay is the next generation of technology for GBS testing, replacing the current culture methodology. This broth-enriched molecular assay provides a rapid report with higher sensitivity compared to culture. The test is ideally suited for testing in late pregnancy.

Support services

Our administrative staff is always on hand to attend to special needs of each office. Prompt couriers and in house billing complement our services. We par with all major insurers and our billing staff can assist your office with questions regarding patients' bills.

ClearPath utilizes a state or the art computer system with a confidential and integrated database. This closed system guarantees security, confidentiality and correlation with previous diagnoses. ClearPath also provides confidential and HIPAA compliant web-based access to your diagnoses.
ClearPath Diagnostics  600 East Genesee Street, Suite 305,  Syracuse, NY 13202
Phone: (315) 234-3300  Toll Free: (866) 310-2406  Fax: (315) 234-3305
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