FREQUENTLY ASKED QUESTIONS
How can a patient's specimen be referred to ClearPath Diagnostics?
A relationship needs to be established between the patient's physician and ClearPath Diagnostics. The patient can ask their physician to send their specimen to ClearPath Diagnostics. The physician, if not already using ClearPath Diagnostics, may contact the main office at (315) 234-3300 or toll-free at (866) 310-2406 to assure courier service or proper transportation.

With which payers is ClearPath Diagnostics in-network?
Click here to access the full list of payers with which we are in-network.

What type of specimens does ClearPath Diagnostics accept?
Cytology: ThinPrep® Pap specimens, non-gynecological specimens to include urines, body fluids and fine needle aspirations.
Pathology: Tissue samples from all sites.

What type of ancillary testing does ClearPath Diagnostics perform? Special studies: Hologic Gen-Probe® APTIMA® assay for Human papillomavirus (HPV) testing, Hologic Gen-Probe assay for GC/Chlamydia and Trichomonas vaginalis, AffirmTM analysis for Candida species, Gardnerella vaginalis, and Trichomonas vaginalis, illumigene® Group B Streptococcus (GBS) testing, illumigene® HSV 1&2 testing, OneSwab® PCR testing, immunohistochemistry, special stains and in situ hybridization.

What information should accompany a specimen that is submitted to ClearPath Diagnostics?
A completed ClearPath Diagnostics requisition form: How do I collect a specimen for cytology submission?
Our Specimen Collection Manual is here.

How does a specimen get to ClearPath Diagnostics?
We provide collection materials and professional, courteous next day or rush courier service for all specimens. Rush service is available from 8:00 a.m. - 3:00 p.m., Monday through Friday. Please contact (315) 234-3300 or toll-free at (866) 310-2406 for more information.

How do I order ClearPath Diagnostics supplies?
The supply order form is available here. Completed forms should be faxed to us at (315) 234-3305.

Does ClearPath Diagnostics offer frozen section analysis?
Yes. We have frozen section capability at our main location and at Medical Center West in Camillus, NY. Contact us at (315) 234-3300 to schedule cases. Our courier service will pick up the specimen at the time needed.

Does ClearPath Diagnostics offer special stains?
Yes. We offer Acid Fast, Alcian Blue, Amyloid, Bacteria, Elastic, Giemsa, GMS, Iron, Mucicarmine, Oil Red O, PAS, PAS-D, PAS-Fungus, Reticulum, Steiner, Toluidine Blue, and Trichrome.

Does ClearPath Diagnostics perform in situ hybridization studies?
Yes. We offer in situ HPV analysis on tissue for both high and low risk subtypes and Her-2/neu by FISH (fluorescence in situ hybridization). We also perform UroVysion® on urine specimens to help detect bladder cancer.

Does ClearPath Diagnostics offer testing for Neisseria gonorrhoeae/Chlamydia trachomatis (GC/Chlamydia) and Trichomonas vaginalis?
Yes. We offer Neisseria gonorrhoeae and Chlamydia trachomatis testing using the highly sensitive Hologic Gen-Probe APTIMA Combo 2® Assay and Trichomonas vaginalis testing using the Hologic Gen-Probe APTIMA Trichomonas vaginalis Assay. These tests can be done using the ThinPrep liquid Pap specimen that is also sent for Pap and HPV analysis. This method allows us to provide up to five results (Pap, HPV, GC/Chlamydia, and Trichomonas) from a single specimen, minimizing specimen handling for collection and transportation. To do these tests in conjunction with a ThinPrep Pap, they must be ordered along with the Pap. GC/Chlamydia and Trichomonas testing cannot be performed after the aliquot for the Pap test has been taken from the vial. Specimen collection and transport information for Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis testing can be found here. We provide the collection and transport material.

Does ClearPath Diagnostics offer testing for Candida species, Gardnerella vaginalis and Trichomonas vaginalis?
Yes. We offer triple testing using Becton Dickinson AffirmTM, VPIII for these agents. This analysis requires a separate vaginal swab. We provide the special swabs and transport system for this test.
Note: The tests that comprise the Affirm Panel cannot be ordered individually. Neisseria gonorrhoeae/Chlamydia trachomatis (GC/Chlamydia) and Trichomonas vaginalis can be ordered individually as detailed in the previous question.

Does ClearPath Diagnostics offer HSV 1&2 testing? Yes. We offer the illumigene® HSV 1&2 test. This innovative molecular test providdes highly sensitive and spcific, rapid results and differentiates bewteen HSV 1&2 on cervical and both mucocutaneous and cutaneous specimens. Specimen collection and transport information for HSV 1&2 can be found here. We provide the collection and transport material.

Does ClearPath Diagnostics offer Group B Streptococcus testing? Yes. We offer the illumigene® test for Group B Streptococcus (GBS). This broth-enriched molecular assay provides a rapid report with higher sensitivity compared to a culture. The test is ideally suited for testing in late pregnancy. Specimen collection and transport information for Group B Streptococcus can be found here. We provide the collection and transport material. Does ClearPath Diagnostics offer PCR testing?
Yes. We offer molecular diagnostic testing through an exclusive arrangement with Medical Diagnostic Laboratories. This advanced polymerase chain reaction (PCR) technique provides a highly sensitive and specific test for numerous pathogens. All tests can be performed from one specimen, collected with MDL's OneSwab®.

Does ClearPath Diagnostics offer immunohistochemistry? If so, what immunostains are available?
Yes. Click here for immunostains listing. This specialized study of tissue and cells is offered to establish diagnoses with full histology technical support. It can be provided with interpretation as a consultation case or without as technical only services.

Does ClearPath Diagnostics accept fine needle aspirations?
Yes. Our courier and next day completion, for the majority of specimens, does apply.

Does ClearPath offer the Tao BrushTM for Endometrial Sampling?
Yes. ClearPath Diagnostics is one of the few laboratories in the country to offer the Tao Brush endometrial sampler. This innovative FDA-approved device allows sampling of the endometrium without the need for cervical dilation. ClearPath's technical process uses formalin fixation in the specially provided vials. The brush tip can be easily clipped from the thin wire handle and placed directly into formalin, providing excellent fixation. Standard H and E evaluation is then available at our facility. ClearPath provides the Tao Brush along with endocervical brushes (used to clear cervical mucus) and specialized formalin vials for our providers who wish to use this device. Instructions for use are found in our collection manual. For more information regarding the Tao Brush, please contact your ClearPath representative or Bruce Bell, Vice President of Sales, bbell@clearpathdiagnostics.com, (410) 353-8045.

How is a case sent to ClearPath Diagnostics for a consultation?
A cover letter with all other pertinent information to the case can be sent to our main address of 600 E. Genesee Street, Suite 305, Syracuse, NY 13202. Any questions, you may contact us at (315) 234-3300 or toll-free at (866) 310-2406.

What specimens can be tested for Human papillomavirus (HPV)?
ThinPrep Pap specimens are approved for testing with Hologic Gen-Probe's APTIMA® Human papillomavirus (HPV) Assay. ThinPrep Pap specimens must be less than four weeks old. There must also be sufficient quantity remaining after processing the pap test to perform the HPV testing. Also, tissue specimens (paraffin embedded) can be tested for high and low risk HPV using in situ hybridization. Tissue specimens are stable indefinitely.

How can the HPV DNA Assay be ordered through ClearPath Diagnostics?
HPV testing can be done reflexively on all ThinPrep Pap samples. Both high and low risk typing are available. A request for HPV testing can be sent with the cytology request for a Pap test on a ThinPrep specimen. For tissue specimens, check the "HPV Tissue Exam" section of the specimen requisition.

How soon are results available from ClearPath Diagnostics?
Under normal circumstances, the average turnaround time for:
  • Pap test results are available within 2-3 working days from receipt of specimen.
  • Reflexive HPV results are available within 24 hours of abnormal Pap sign out.
  • Pap/HPV co-testing results are available within 2-3 working days from receipt of specimen.
  • Non-GYN results are available within 24 hours from receipt of specimen.
  • Surgical pathology results are generally available within 24 hours from receipt of specimen, Monday-Friday.
  • Immunohistochemical stains are quickly processed and can be sent to referring labs within 1 day from receipt.
ClearPath Diagnostics  600 East Genesee Street, Suite 305,  Syracuse, NY 13202
Phone: (315) 234-3300  Toll Free: (866) 310-2406  Fax: (315) 234-3305
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